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Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus
Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic acid (VPA) inhibits initiation of the lytic cycle in EBV-infected B lymphoma cells. While VPA blocks viral lytic gene expression, it induces...
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| Pubblicato in: | mBio |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Microbiology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810481/ https://ncbi.nlm.nih.gov/pubmed/26933051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00113-16 |
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