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Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus

Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic acid (VPA) inhibits initiation of the lytic cycle in EBV-infected B lymphoma cells. While VPA blocks viral lytic gene expression, it induces...

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Gorres, Kelly L., Daigle, Derek, Mohanram, Sudharshan, McInerney, Grace E., Lyons, Danielle E., Miller, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Microbiology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810481/
https://ncbi.nlm.nih.gov/pubmed/26933051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00113-16
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