Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus

Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic acid (VPA) inhibits initiation of the lytic cycle in EBV-infected B lymphoma cells. While VPA blocks viral lytic gene expression, it induces...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:mBio
Autores principales: Gorres, Kelly L., Daigle, Derek, Mohanram, Sudharshan, McInerney, Grace E., Lyons, Danielle E., Miller, George
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810481/
https://ncbi.nlm.nih.gov/pubmed/26933051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00113-16
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares