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Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus

Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic acid (VPA) inhibits initiation of the lytic cycle in EBV-infected B lymphoma cells. While VPA blocks viral lytic gene expression, it induces...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Gorres, Kelly L., Daigle, Derek, Mohanram, Sudharshan, McInerney, Grace E., Lyons, Danielle E., Miller, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810481/
https://ncbi.nlm.nih.gov/pubmed/26933051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00113-16
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