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Retargeting Strategies for Oncolytic Herpes Simplex Viruses
Most of the oncolytic herpes simplex viruses (HSVs) exhibit a high safety profile achieved through attenuation. They carry defects in virulence proteins that antagonize host cell response to the virus, including innate response, apoptosis, authophagy, and depend on tumor cell proliferation. They gro...
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| Pubblicato in: | Viruses |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810253/ https://ncbi.nlm.nih.gov/pubmed/26927159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8030063 |
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