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A Strategy for Cultivation of Retargeted Oncolytic Herpes Simplex Viruses in Non-cancer Cells

The oncolytic herpes simplex virus (HSV) that has been approved for clinical practice and those HSVs in clinical trials are attenuated viruses, often with the neurovirulence gene γ(1)34.5 and additional genes deleted. One strategy to engineer nonattenuated oncolytic HSVs consists of retargeting the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Leoni, Valerio, Gatta, Valentina, Casiraghi, Costanza, Nicosia, Alfredo, Petrovic, Biljana, Campadelli-Fiume, Gabriella
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411604/
https://ncbi.nlm.nih.gov/pubmed/28250120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00067-17
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