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Dual Ligand Insertion in gB and gD of Oncolytic Herpes Simplex Viruses for Retargeting to a Producer Vero Cell Line and to Cancer Cells

Oncolytic viruses gain cancer specificity in several ways. Like the majority of viruses, they grow better in cancer cells that are defective in mounting the host response to viruses. Often, they are attenuated by deletion or mutation of virulence genes that counteract the host response or are natura...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Petrovic, Biljana, Leoni, Valerio, Gatta, Valentina, Zaghini, Anna, Vannini, Andrea, Campadelli-Fiume, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827396/
https://ncbi.nlm.nih.gov/pubmed/29263257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02122-17
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