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Retargeting Strategies for Oncolytic Herpes Simplex Viruses

Most of the oncolytic herpes simplex viruses (HSVs) exhibit a high safety profile achieved through attenuation. They carry defects in virulence proteins that antagonize host cell response to the virus, including innate response, apoptosis, authophagy, and depend on tumor cell proliferation. They gro...

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Bibliografske podrobnosti
izdano v:Viruses
Main Authors: Campadelli-Fiume, Gabriella, Petrovic, Biljana, Leoni, Valerio, Gianni, Tatiana, Avitabile, Elisa, Casiraghi, Costanza, Gatta, Valentina
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810253/
https://ncbi.nlm.nih.gov/pubmed/26927159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8030063
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