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Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine
Thirty-two congeneric rigid adenine nucleoside derivatives containing a North (N)-methanocarba ribose substitution and a 2-arylethynyl group either enhanced (up to 760% of control) or inhibited [(125)I] methyl (1R,2S,3S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate (RTI-55) bind...
Enregistré dans:
Publié dans: | J Pharmacol Exp Ther |
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Auteurs principaux: | , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4809312/ https://ncbi.nlm.nih.gov/pubmed/26813929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.229666 |
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