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Phospholipase D Elevates the Level of MDM2 and Suppresses DNA Damage-Induced Increases in p53
Phospholipase D (PLD) has been reported to generate survival signals that prevent apoptosis induced by serum withdrawal. We have now found that elevated expression of PLD also suppresses DNA damage-induced apoptosis. Since DNA damage-induced apoptosis is often mediated by p53, we examined the effect...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology
2004
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC480910/ https://ncbi.nlm.nih.gov/pubmed/15199126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.5677-5686.2004 |
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