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Cytotoxic T cells use mechanical force to potentiate target cell killing
The immunological synapse formed between a cytotoxic T lymphocyte (CTL) and an infected or transformed target cell is a physically active structure capable of exerting mechanical force. Here, we investigated whether synaptic forces promote the destruction of target cells. CTLs kill by secreting toxi...
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| 出版年: | Cell |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4808403/ https://ncbi.nlm.nih.gov/pubmed/26924577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.01.021 |
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