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Centrioles control the capacity, but not the specificity, of cytotoxic T cell killing
Immunological synapse formation between cytotoxic T lymphocytes (CTLs) and the target cells they aim to destroy is accompanied by reorientation of the CTL centrosome to a position beneath the synaptic membrane. Centrosome polarization is thought to enhance the potency and specificity of killing by d...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7049148/ https://ncbi.nlm.nih.gov/pubmed/32041868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913220117 |
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