Pharmacokinetics of Rifampin, Isoniazid, Pyrazinamide, and Ethambutol in Infants Dosed According to Revised WHO-Recommended Treatment Guidelines

There are limited pharmacokinetic data for use of the first-line antituberculosis drugs during infancy (<12 months of age), when drug disposition may differ. Intensive pharmacokinetic sampling was performed in infants routinely receiving antituberculosis treatment, including rifampin, isoniazid,...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Bekker, A., Schaaf, H. S., Draper, H. R., van der Laan, L., Murray, S., Wiesner, L., Donald, P. R., McIlleron, H. M., Hesseling, A. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808214/
https://ncbi.nlm.nih.gov/pubmed/26810651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02600-15
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