Acyclovir diphosphate dimyristoylglycerol: a phospholipid prodrug with activity against acyclovir-resistant herpes simplex virus.

Infection with herpes simplex viruses (HSVs) resistant to treatment with acyclovir (9-[(2-hydroxyethoxy)-methyl]guanine, Zovirax) is a growing clinical problem in patients with AIDS and other immunosuppressed states. Most virus isolates resistant to acyclovir are deficient or defective in virally co...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Hostetler, K Y, Parker, S, Sridhar, C N, Martin, M J, Li, J L, Stuhmiller, L M, van Wijk, G M, van den Bosch, H, Gardner, M F, Aldern, K A
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1993
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48079/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265634/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11835
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