Acyclovir diphosphate dimyristoylglycerol: a phospholipid prodrug with activity against acyclovir-resistant herpes simplex virus.

Infection with herpes simplex viruses (HSVs) resistant to treatment with acyclovir (9-[(2-hydroxyethoxy)-methyl]guanine, Zovirax) is a growing clinical problem in patients with AIDS and other immunosuppressed states. Most virus isolates resistant to acyclovir are deficient or defective in virally co...

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Autores principales: Hostetler, K Y, Parker, S, Sridhar, C N, Martin, M J, Li, J L, Stuhmiller, L M, van Wijk, G M, van den Bosch, H, Gardner, M F, Aldern, K A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC48079/
https://ncbi.nlm.nih.gov/pubmed/8265634
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