Thymidine kinase not required for antiviral activity of acyclovir against mouse cytomegalovirus.
Previous studies of herpesvirus infections have indicated that a virus-specified thymidine kinase is required for the initial phosphorylation of acyclovir [acycloguanosine or 9-(2-hydroxyethoxymethyl)guanine] in the formation of acycloguanosine triphosphate. The latter compound accumulates in infect...
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| Udgivet i: | J Virol |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1981
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6270357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.39.3.889-893.1981 |
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