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Thymidine kinase not required for antiviral activity of acyclovir against mouse cytomegalovirus.

Previous studies of herpesvirus infections have indicated that a virus-specified thymidine kinase is required for the initial phosphorylation of acyclovir [acycloguanosine or 9-(2-hydroxyethoxymethyl)guanine] in the formation of acycloguanosine triphosphate. The latter compound accumulates in infect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Burns, W H, Wingard, J R, Bender, W J, Saral, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC171322/
https://ncbi.nlm.nih.gov/pubmed/6270357
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