Efficacy of acyclovir against mouse cytomegalovirus in vivo.

Acyclovir reduced mortality and organ virus titers in mice inoculated intraperitoneally with 10 50% lethal doses of mouse cytomegalovirus. This susceptibility to acyclovir of a herpesvirus which lacks thymidine kinase is surprising. Alternative phosphorylating enzymes may account for this susceptibi...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Wingard, J R, Bender, W J, Saral, R, Burns, W H
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1981
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181681/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6269490/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.20.2.275
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