Efficacy of acyclovir against mouse cytomegalovirus in vivo.

Acyclovir reduced mortality and organ virus titers in mice inoculated intraperitoneally with 10 50% lethal doses of mouse cytomegalovirus. This susceptibility to acyclovir of a herpesvirus which lacks thymidine kinase is surprising. Alternative phosphorylating enzymes may account for this susceptibi...

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Bibliographic Details
Main Authors: Wingard, J R, Bender, W J, Saral, R, Burns, W H
Format: Artigo
Language:Inglês
Published: 1981
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC181681/
https://ncbi.nlm.nih.gov/pubmed/6269490
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