Nucleotide sequence changes in thymidine kinase gene of herpes simplex virus type 2 clones from an isolate of a patient treated with acyclovir.

To identify the nucleotide changes that occur in drug-induced thymidine kinase (TK) mutants of herpes simplex virus type 2 (HSV-2), we compared the nucleotide sequences of the tk genes of two mutant HSV-2 clones isolated from a patient who had been treated with acyclovir [9-(2-hydroxyethoxymethyl)gu...

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Autores principales: Kit, S, Sheppard, M, Ichimura, H, Nusinoff-Lehrman, S, Ellis, M N, Fyfe, J A, Otsuka, H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC174976/
https://ncbi.nlm.nih.gov/pubmed/2829709
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