Nucleotide sequence changes in thymidine kinase gene of herpes simplex virus type 2 clones from an isolate of a patient treated with acyclovir.

To identify the nucleotide changes that occur in drug-induced thymidine kinase (TK) mutants of herpes simplex virus type 2 (HSV-2), we compared the nucleotide sequences of the tk genes of two mutant HSV-2 clones isolated from a patient who had been treated with acyclovir [9-(2-hydroxyethoxymethyl)gu...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Kit, S, Sheppard, M, Ichimura, H, Nusinoff-Lehrman, S, Ellis, M N, Fyfe, J A, Otsuka, H
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1987
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829709/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.10.1483
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