RAGE and TGF-β1 Cross-Talk Regulate Extracellular Matrix Turnover and Cytokine Synthesis in AGEs Exposed Fibroblast Cells

AGEs accumulation in the skin affects extracellular matrix (ECM) turnover and triggers diabetes associated skin conditions and accelerated skin aging. The receptor of AGEs (RAGE) has an essential contribution to cellular dysfunction driven by chronic inflammatory responses while TGF-β1 is critical i...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Serban, Andreea Iren, Stanca, Loredana, Geicu, Ovidiu Ionut, Munteanu, Maria Cristina, Dinischiotu, Anca
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807770/
https://ncbi.nlm.nih.gov/pubmed/27015414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152376
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