YAP Induces Human Naive Pluripotency

The human naive pluripotent stem cell (PSC) state, corresponding to a pre-implantation stage of development, has been difficult to capture and sustain in vitro. We report that the Hippo pathway effector YAP is nuclearly localized in the inner cell mass of human blastocysts. Overexpression of YAP in...

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Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Qin, Han, Hejna, Miroslav, Liu, Yanxia, Percharde, Michelle, Wossidlo, Mark, Blouin, Laure, Durruthy-Durruthy, Jens, Wong, Priscilla, Qi, Zhongxia, Yu, Jingwei, Qi, Lei S., Sebastiano, Vittorio, Song, Jun S., Ramalho-Santos, Miguel
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807727/
https://ncbi.nlm.nih.gov/pubmed/26947063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.036
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