YAP Induces Human Naive Pluripotency

The human naive pluripotent stem cell (PSC) state, corresponding to a pre-implantation stage of development, has been difficult to capture and sustain in vitro. We report that the Hippo pathway effector YAP is nuclearly localized in the inner cell mass of human blastocysts. Overexpression of YAP in...

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Опубликовано в: :Cell Rep
Главные авторы: Qin, Han, Hejna, Miroslav, Liu, Yanxia, Percharde, Michelle, Wossidlo, Mark, Blouin, Laure, Durruthy-Durruthy, Jens, Wong, Priscilla, Qi, Zhongxia, Yu, Jingwei, Qi, Lei S., Sebastiano, Vittorio, Song, Jun S., Ramalho-Santos, Miguel
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807727/
https://ncbi.nlm.nih.gov/pubmed/26947063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.036
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