YAP Induces Human Naive Pluripotency

The human naive pluripotent stem cell (PSC) state, corresponding to a pre-implantation stage of development, has been difficult to capture and sustain in vitro. We report that the Hippo pathway effector YAP is nuclearly localized in the inner cell mass of human blastocysts. Overexpression of YAP in...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Qin, Han, Hejna, Miroslav, Liu, Yanxia, Percharde, Michelle, Wossidlo, Mark, Blouin, Laure, Durruthy-Durruthy, Jens, Wong, Priscilla, Qi, Zhongxia, Yu, Jingwei, Qi, Lei S., Sebastiano, Vittorio, Song, Jun S., Ramalho-Santos, Miguel
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807727/
https://ncbi.nlm.nih.gov/pubmed/26947063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.036
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