YAP Induces Human Naive Pluripotency

The human naive pluripotent stem cell (PSC) state, corresponding to a pre-implantation stage of development, has been difficult to capture and sustain in vitro. We report that the Hippo pathway effector YAP is nuclearly localized in the inner cell mass of human blastocysts. Overexpression of YAP in...

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發表在:Cell Rep
Main Authors: Qin, Han, Hejna, Miroslav, Liu, Yanxia, Percharde, Michelle, Wossidlo, Mark, Blouin, Laure, Durruthy-Durruthy, Jens, Wong, Priscilla, Qi, Zhongxia, Yu, Jingwei, Qi, Lei S., Sebastiano, Vittorio, Song, Jun S., Ramalho-Santos, Miguel
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807727/
https://ncbi.nlm.nih.gov/pubmed/26947063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.036
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