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Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming

Pluripotent stem cells are derived from culture of early embryos or the germline and can be induced by reprogramming of somatic cells. Barriers to reprogramming that stabilize the differentiated state and have tumor suppression functions are expected to exist. However, we have a limited understandin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qin, Han, Blaschke, Kathryn, Wei, Grace, Ohi, Yuki, Blouin, Laure, Qi, Zhongxia, Yu, Jingwei, Yeh, Ru-Fang, Hebrok, Matthias, Ramalho-Santos, Miguel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315209/
https://ncbi.nlm.nih.gov/pubmed/22286172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds023
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