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Incomplete DNA methylation underlies a transcriptional memory of the somatic cell in human iPS cells

Human induced pluripotent stem (iPS) cells are remarkably similar to embryonic stem (ES) cells, but recent reports suggest that there may be important differences between them. We performed a systematic comparison of human iPS cells generated from hepatocytes (representative of endoderm), skin fibro...

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Main Authors: Ohi, Yuki, Qin, Han, Hong, Chibo, Blouin, Laure, Polo, Jose M., Guo, Tingxia, Qi, Zhongxia, Downey, Sara L., Manos, Philip D., Rossi, Derrick J., Yu, Jingwei, Hebrok, Matthias, Hochedlinger, Konrad, Costello, Joseph F., Song, Jun S., Ramalho-Santos, Miguel
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987913/
https://ncbi.nlm.nih.gov/pubmed/21499256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2239
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