Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate

Bone degenerative pathologies like osteoporosis may be initiated by age-related shifts in anabolic and catabolic responses that control bone homeostasis. Here we show that sulforaphane (SFN), a naturally occurring isothiocyanate, promotes osteoblast differentiation by epigenetic mechanisms. SFN enha...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Thaler, Roman, Maurizi, Antonio, Roschger, Paul, Sturmlechner, Ines, Khani, Farzaneh, Spitzer, Silvia, Rumpler, Monika, Zwerina, Jochen, Karlic, Heidrun, Dudakovic, Amel, Klaushofer, Klaus, Teti, Anna, Rucci, Nadia, Varga, Franz, van Wijnen, Andre J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807263/
https://ncbi.nlm.nih.gov/pubmed/26757819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678235
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker