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DMSO is a strong inducer of DNA hydroxymethylation in pre-osteoblastic MC3T3-E1 cells
Artificial induction of active DNA demethylation appears to be a possible and useful strategy in molecular biology research and therapy development. Dimethyl sulfoxide (DMSO) was shown to cause phenotypic changes in embryonic stem cells altering the genome-wide DNA methylation profiles. Here we repo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398991/ https://ncbi.nlm.nih.gov/pubmed/22507896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.20163 |
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