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Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1–3

Perilipins (PLINs) play a key role in energy storage by orchestrating the activity of lipases on the surface of lipid droplets. Failure of this activity results in severe metabolic disease in humans. Unlike all other lipid droplet-associated proteins, PLINs localize almost exclusively to the phospho...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rowe, Emily R., Mimmack, Michael L., Barbosa, Antonio D., Haider, Afreen, Isaac, Iona, Ouberai, Myriam M., Thiam, Abdou Rachid, Patel, Satish, Saudek, Vladimir, Siniossoglou, Symeon, Savage, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807253/
https://ncbi.nlm.nih.gov/pubmed/26742848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691048
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