Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1–3

Perilipins (PLINs) play a key role in energy storage by orchestrating the activity of lipases on the surface of lipid droplets. Failure of this activity results in severe metabolic disease in humans. Unlike all other lipid droplet-associated proteins, PLINs localize almost exclusively to the phospho...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Rowe, Emily R., Mimmack, Michael L., Barbosa, Antonio D., Haider, Afreen, Isaac, Iona, Ouberai, Myriam M., Thiam, Abdou Rachid, Patel, Satish, Saudek, Vladimir, Siniossoglou, Symeon, Savage, David B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Membrane Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807253/
https://ncbi.nlm.nih.gov/pubmed/26742848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691048
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