Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1–3

Perilipins (PLINs) play a key role in energy storage by orchestrating the activity of lipases on the surface of lipid droplets. Failure of this activity results in severe metabolic disease in humans. Unlike all other lipid droplet-associated proteins, PLINs localize almost exclusively to the phospho...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Rowe, Emily R., Mimmack, Michael L., Barbosa, Antonio D., Haider, Afreen, Isaac, Iona, Ouberai, Myriam M., Thiam, Abdou Rachid, Patel, Satish, Saudek, Vladimir, Siniossoglou, Symeon, Savage, David B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807253/
https://ncbi.nlm.nih.gov/pubmed/26742848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691048
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