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A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets

How proteins are targeted to lipid droplets (LDs) and distinguish the LD surface from the surfaces of other organelles is poorly understood, but many contain predicted amphipathic helices (AHs) that are involved in targeting. We have focused on human perilipin 4 (Plin4), which contains an AH that is...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Čopič, Alenka, Antoine-Bally, Sandra, Giménez-Andrés, Manuel, La Torre Garay, César, Antonny, Bruno, Manni, Marco M., Pagnotta, Sophie, Guihot, Jeanne, Jackson, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889406/
https://ncbi.nlm.nih.gov/pubmed/29626194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03717-8
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