A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets

How proteins are targeted to lipid droplets (LDs) and distinguish the LD surface from the surfaces of other organelles is poorly understood, but many contain predicted amphipathic helices (AHs) that are involved in targeting. We have focused on human perilipin 4 (Plin4), which contains an AH that is...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Čopič, Alenka, Antoine-Bally, Sandra, Giménez-Andrés, Manuel, La Torre Garay, César, Antonny, Bruno, Manni, Marco M., Pagnotta, Sophie, Guihot, Jeanne, Jackson, Catherine L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889406/
https://ncbi.nlm.nih.gov/pubmed/29626194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03717-8
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