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Assessment of direct gating and allosteric modulatory effects of meprobamate in recombinant GABA(A) receptors
Meprobamate is a schedule II anxiolytic and the primary metabolite of the muscle relaxant carisoprodol. Meprobamate modulates GABA(A) (γ-aminobutyric acid type A) receptors, and has barbiturate-like activity. To gain insight into its actions, we have conducted a series of studies using recombinant G...
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| Publicat a: | Eur J Pharmacol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806799/ https://ncbi.nlm.nih.gov/pubmed/26872987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.02.031 |
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