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Assessment of direct gating and allosteric modulatory effects of meprobamate in recombinant GABA(A) receptors

Meprobamate is a schedule II anxiolytic and the primary metabolite of the muscle relaxant carisoprodol. Meprobamate modulates GABA(A) (γ-aminobutyric acid type A) receptors, and has barbiturate-like activity. To gain insight into its actions, we have conducted a series of studies using recombinant G...

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Bibliografiska uppgifter
I publikationen:Eur J Pharmacol
Huvudupphovsmän: Kumar, Manish, Dillon, Glenn H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806799/
https://ncbi.nlm.nih.gov/pubmed/26872987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.02.031
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