YAP induces cisplatin resistance through activation of autophagy in human ovarian carcinoma cells

OBJECTIVE: To identify the role of YAP in cisplatin resistance in human ovarian cancer cells and in the regulation of autophagy in these cancer cells. MATERIALS AND METHODS: The cisplatin-sensitive OV2008 parental cell line and its cisplatin-resistant variant C13K were cultured. RNA interference was...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Xiao, Lan, Shi, Xiao-Yan, Zhang, Ying, Zhu, Ying, Zhu, Lin, Tian, Wang, Zhu, Bing-Kun, Wei, Zhao-Lian
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806764/
https://ncbi.nlm.nih.gov/pubmed/27073322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S102837
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