Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma

Cisplatin resistance is a major problem affecting ovarian carcinoma treatment. NF-E2-related factor 2 (Nrf2), a nuclear transcription factor, plays an important role in chemotherapy resistance. However, the underlying mechanism by which Nrf2 mediates cisplatin chemoresistance is unclear. Methods: Th...

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Bibliografiske detaljer
Main Authors: Bao, Ling-Jie, Jaramillo, Melba C, Zhang, Zhen-Bo, Zheng, Yun-Xi, Yao, Ming, Zhang, Donna D, Yi, Xiao-Fang
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014230/
https://ncbi.nlm.nih.gov/pubmed/24817946
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