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Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment
Caspase-2 plays an important role in apoptosis induced by several stimuli, including oxidative stress. However, the subcellular localization of caspase-2, particularly its presence in the mitochondria, is unclear. It is also not known if cytosolic caspase-2 translocates to the mitochondria to trigge...
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| Udgivet i: | Cell Death Discov |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806400/ https://ncbi.nlm.nih.gov/pubmed/27019748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.5 |
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