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ER–mitochondria contacts promote mitochondrial-derived compartment biogenesis

Mitochondria are dynamic organelles with essential roles in signaling and metabolism. We recently identified a cellular structure called the mitochondrial-derived compartment (MDC) that is generated from mitochondria in response to amino acid overabundance stress. How cells form MDCs is unclear. Her...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: English, Alyssa M., Schuler, Max-Hinderk, Xiao, Tianyao, Kornmann, Benoît, Shaw, Janet M., Hughes, Adam L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588143/
https://ncbi.nlm.nih.gov/pubmed/33090183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202002144
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