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Vps13-Mcp1 interact at vacuole–mitochondria interfaces and bypass ER–mitochondria contact sites

Membrane contact sites between endoplasmic reticulum (ER) and mitochondria, mediated by the ER–mitochondria encounter structure (ERMES) complex, are critical for mitochondrial homeostasis and cell growth. Defects in ERMES can, however, be bypassed by point mutations in the endosomal protein Vps13 or...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: John Peter, Arun T., Herrmann, Beatrice, Antunes, Diana, Rapaport, Doron, Dimmer, Kai Stefan, Kornmann, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626531/
https://ncbi.nlm.nih.gov/pubmed/28864540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201610055
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