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Vps13-Mcp1 interact at vacuole–mitochondria interfaces and bypass ER–mitochondria contact sites

Membrane contact sites between endoplasmic reticulum (ER) and mitochondria, mediated by the ER–mitochondria encounter structure (ERMES) complex, are critical for mitochondrial homeostasis and cell growth. Defects in ERMES can, however, be bypassed by point mutations in the endosomal protein Vps13 or...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: John Peter, Arun T., Herrmann, Beatrice, Antunes, Diana, Rapaport, Doron, Dimmer, Kai Stefan, Kornmann, Benoît
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626531/
https://ncbi.nlm.nih.gov/pubmed/28864540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201610055
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