Loss of Caspase-2-dependent Apoptosis Induces Autophagy after Mitochondrial Oxidative Stress in Primary Cultures of Young Adult Cortical Neurons

Mitochondrial dysfunctions have been associated with neuronal apoptosis and are characteristic of neurodegenerative conditions. Caspases play a central role in apoptosis; however, their involvement in mitochondrial dysfunction-induced neuronal apoptosis remains elusive. In the present report using r...

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Bibliographic Details
Main Authors: Tiwari, Meenakshi, Lopez-Cruzan, Marisa, Morgan, William W., Herman, Brian
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048733/
https://ncbi.nlm.nih.gov/pubmed/21216964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163824
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