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Loss of Caspase-2-dependent Apoptosis Induces Autophagy after Mitochondrial Oxidative Stress in Primary Cultures of Young Adult Cortical Neurons

Mitochondrial dysfunctions have been associated with neuronal apoptosis and are characteristic of neurodegenerative conditions. Caspases play a central role in apoptosis; however, their involvement in mitochondrial dysfunction-induced neuronal apoptosis remains elusive. In the present report using r...

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Detalhes bibliográficos
Main Authors: Tiwari, Meenakshi, Lopez-Cruzan, Marisa, Morgan, William W., Herman, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048733/
https://ncbi.nlm.nih.gov/pubmed/21216964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163824
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