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Loss of Caspase-2-dependent Apoptosis Induces Autophagy after Mitochondrial Oxidative Stress in Primary Cultures of Young Adult Cortical Neurons

Mitochondrial dysfunctions have been associated with neuronal apoptosis and are characteristic of neurodegenerative conditions. Caspases play a central role in apoptosis; however, their involvement in mitochondrial dysfunction-induced neuronal apoptosis remains elusive. In the present report using r...

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Autors principals: Tiwari, Meenakshi, Lopez-Cruzan, Marisa, Morgan, William W., Herman, Brian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048733/
https://ncbi.nlm.nih.gov/pubmed/21216964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163824
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