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Dysregulated autophagy contributes to caspase-dependent neuronal apoptosis

Autophagy is a regulated, intracellular degradation process that delivers unnecessary or dysfunctional cargo to the lysosome. Autophagy has been viewed as an adaptive survival response to various stresses, whereas in other cases, it promotes cell death. Therefore, both deficient and excessive autoph...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Chung, Yuhyun, Lee, Juhyung, Jung, Shinae, Lee, Yangsin, Cho, Jin Won, Oh, Young J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289995/
https://ncbi.nlm.nih.gov/pubmed/30538224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1229-y
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