Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway

Hedgehog (Hh) is a critical regulator of adipogenesis. Extracellular vesicles are natural Hh carriers, as illustrated by activated/apoptotic lymphocytes specifically shedding microparticles (MP) bearing the morphogen (MP(Hh+)). We show that MP(Hh+) inhibit adipocyte differentiation and orientate mes...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Fleury, Audrey, Hoch, Lucile, Martinez, M. Carmen, Faure, Hélène, Taddei, Maurizio, Petricci, Elena, Manetti, Fabrizio, Girard, Nicolas, Mann, André, Jacques, Caroline, Larghero, Jérôme, Ruat, Martial, Andriantsitohaina, Ramaroson, Le Lay, Soazig
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806302/
https://ncbi.nlm.nih.gov/pubmed/27010359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23479
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