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Manufacturing of recombinant adeno-associated viral vectors for clinical trials

The ability to elicit robust and long-term transgene expression in vivo together with minimal immunogenicity and little to no toxicity are only a few features that make recombinant adeno-associated virus (rAAV) vectors ideally suited for many gene therapy applications. Successful preclinical studies...

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Detalles Bibliográficos
Publicado en:Mol Ther Methods Clin Dev
Main Authors: Clément, Nathalie, Grieger, Joshua C
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804725/
https://ncbi.nlm.nih.gov/pubmed/27014711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.2
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