HIV-1 Nucleocapsid mimics the membrane adaptor Syntenin to gain access to ESCRTs and promote virus budding

HIV-1 recruits cellular Endosomal Sorting Complexes Required for Transport (ESCRTs) to bud virions from the membrane. Disruption of the viral nucleocapsid (NC) domain integrity affects HIV-1 budding. However, the molecular mechanisms of NC’s involvement in HIV budding remain unclear. We find that NC...

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Pubblicato in:Cell Host Microbe
Autori principali: Sette, Paola, O’Connor, Sarah K., Yerramilli, V. Siddartha, Dussupt, Vincent, Nagashima, Kunio, Chutiraka, Kasana, Lingappa, Jaisri, Scarlata, Suzanne, Bouamr, Fadila
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804359/
https://ncbi.nlm.nih.gov/pubmed/26962944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.02.004
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