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HIV-1 Nucleocapsid mimics the membrane adaptor Syntenin to gain access to ESCRTs and promote virus budding
HIV-1 recruits cellular Endosomal Sorting Complexes Required for Transport (ESCRTs) to bud virions from the membrane. Disruption of the viral nucleocapsid (NC) domain integrity affects HIV-1 budding. However, the molecular mechanisms of NC’s involvement in HIV budding remain unclear. We find that NC...
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| Publicado no: | Cell Host Microbe |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4804359/ https://ncbi.nlm.nih.gov/pubmed/26962944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.02.004 |
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