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Nickel-Catalyzed Cross-Coupling of Chromene Acetals and Boronic Acids

A modular and highly efficient protocol for the synthesis of 2-aryl- and heteroaryl-2H-chromenes is described. Under base-free conditions, readily accessible 2-ethoxy-2H-chromenes undergo C(sp(3))–O activation and C(sp(3))–C bond formation in the presence of an inexpensive nickel catalyst and boroni...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Graham, Thomas J. A., Doyle, Abigail G.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804347/
https://ncbi.nlm.nih.gov/pubmed/22385385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300364s
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