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Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules

Amyloids are cross-β-sheet fibrillar aggregates, associated with various human diseases and native functions such as protein/peptide hormone storage inside secretory granules of neuroendocrine cells. In the current study, using amyloid detecting agents, we show that growth hormone (GH) could be stor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Jacob, Reeba S., Das, Subhadeep, Ghosh, Saikat, Anoop, Arunagiri, Jha, Narendra Nath, Khan, Tuhin, Singru, Praful, Kumar, Ashutosh, Maji, Samir K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804206/
https://ncbi.nlm.nih.gov/pubmed/27004850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23370
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