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Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14: RELEVANCE TO ITS STORAGE AND SECRETION

The storage of protein/peptide hormones within subcellular compartments and subsequent release are crucial for their native function, and hence these processes are intricately regulated in mammalian systems. Several peptide hormones were recently suggested to be stored as amyloids within endocrine s...

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Bibliographic Details
Main Authors: Anoop, Arunagiri, Ranganathan, Srivastav, Dhaked, Bhagwan Das, Jha, Narendra Nath, Pratihar, Supriya, Ghosh, Saikat, Sahay, Shruti, Kumar, Santosh, Das, Subhadeep, Kombrabail, Mamata, Agarwal, Kumud, Jacob, Reeba S., Singru, Praful, Bhaumik, Prasenjit, Padinhateeri, Ranjith, Kumar, Ashutosh, Maji, Samir K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059132/
https://ncbi.nlm.nih.gov/pubmed/24782311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548354
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