Molecular Interpretation of ACTH-β-Endorphin Coaggregation: Relevance to Secretory Granule Biogenesis

Peptide/protein hormones could be stored as non-toxic amyloid-like structures in pituitary secretory granules. ACTH and β-endorphin are two of the important peptide hormones that get co-stored in the pituitary secretory granules. Here, we study molecular interactions between ACTH and β-endorphin and...

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Bibliographic Details
Main Authors: Ranganathan, Srivastav, Singh, Pradeep K., Singh, Uday, Singru, Praful S., Padinhateeri, Ranjith, Maji, Samir K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293876/
https://ncbi.nlm.nih.gov/pubmed/22403619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031924
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