Identification of small molecule agonists of human relaxin family receptor 1 (RXFP1) by utilizing a homogenous cell-based cAMP assay

The relaxin hormone is involved in a variety of biological functions including female reproduction and parturition, regulation of cardiovascular, renal, pulmonary, and hepatic functions. It regulates extracellular matrix remodeling, cell invasiveness, proliferation, differentiation, and overall tiss...

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Veröffentlicht in:J Biomol Screen
Hauptverfasser: Chen, Catherine Z., Southall, Noel, Xiao, Jingbo, Marugan, Juan J., Ferrer, Marc, Hu, Xin, Jones, Raisa E., Feng, Shu, Agoulnik, Irina U., Zheng, Wei, Agoulnik, Alexander I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804196/
https://ncbi.nlm.nih.gov/pubmed/23212924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112469406
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