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Application of Rigidity Theory to the Thermostabilization of Lipase A from Bacillus subtilis
Protein thermostability is a crucial factor for biotechnological enzyme applications. Protein engineering studies aimed at improving thermostability have successfully applied both directed evolution and rational design. However, for rational approaches, the major challenge remains the prediction of...
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| Veröffentlicht in: | PLoS Comput Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4803202/ https://ncbi.nlm.nih.gov/pubmed/27003415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004754 |
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