Contribution of single amino acid and codon substitutions to the production and secretion of a lipase by Bacillus subtilis

Abstract Background Bacillus subtilis produces and secretes proteins in amounts of up to 20 g/l under optimal conditions. However, protein production can be challenging if transcription and cotranslational secretion are negatively affected, or the target protein is degraded by extracellular protease...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pia Skoczinski, Kristina Volkenborn, Alexander Fulton, Anuseema Bhadauriya, Christina Nutschel, Holger Gohlke, Andreas Knapp, Karl-Erich Jaeger
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-09-01
Colecção:Microbial Cell Factories
Assuntos:
Bacillus subtilis
Lipase
Protein production
Secretion
Optimization
Acesso em linha:http://link.springer.com/article/10.1186/s12934-017-0772-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados